4-Nitro-2-(trifluoromethyl)benzoyl chloride
4-NITRO-2-(TRIFLUOROMETHYL)BENZOIC ACID
CAS: 98187-15-6
Molecular Formula: C8H3ClF3NO3
4-Nitro-2-(trifluoromethyl)benzoyl chloride - Names and Identifiers
4-Nitro-2-(trifluoromethyl)benzoyl chloride - Physico-chemical Properties
| Molecular Formula | C8H3ClF3NO3 |
| Molar Mass | 253.56 |
| Density | 1.573±0.06 g/cm3(Predicted) |
| Melting Point | 138-142°C(lit.) |
| Boling Point | 283.2±40.0 °C(Predicted) |
4-Nitro-2-(trifluoromethyl)benzoyl chloride - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| Hazard Note | Irritant |
4-Nitro-2-(trifluoromethyl)benzoyl chloride - References
| introduction | 4-nitro -2-(trifluoromethyl) benzoic acid is white to light yellow crystal powder, density: 1.596g/cm3, boiling point: 321.4 c at 760mmHg, melting point: 138-142 c (lit.). It is an important pharmaceutical and pesticide intermediate, which can be prepared by a variety of synthetic routes. |
| use | 4-nitro-2-(trifluoromethyl) benzoic acid is a white to light yellow crystal powder, which is mainly used as an important pharmaceutical and pesticide intermediate. |
| preparation | add 5g of 2-trifluoromethylbenzocyanine to the three-mouth bottle, add 10 mL of nitrating agent dropwise, raise the temperature to 70°C, stir magnetically for 3 h, and end the reaction. Add 30 ml of water, separate the liquid, take the organic layer, the water layer is extracted once with 30 ml of ethyl acetate, combine the organic phase, dry with anhydrous sodium sulfate, and spin steaming to obtain 6.5 g solid, 4-nitro-2-(trifluoromethyl) benzoic acid. |
Last Update：2024-04-09 15:17:30
